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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FREM3
All Species:
16.67
Human Site:
T643
Identified Species:
52.38
UniProt:
P0C091
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P0C091
NP_001161707
2135
237764
T643
G
L
Y
E
K
V
V
T
E
W
L
Q
R
D
I
Chimpanzee
Pan troglodytes
XP_517461
2289
255014
T793
G
L
Y
E
K
V
V
T
E
W
L
Q
R
D
I
Rhesus Macaque
Macaca mulatta
XP_001092507
2276
253244
T780
G
L
Y
E
K
V
V
T
E
W
L
Q
R
D
I
Dog
Lupus familis
XP_543127
3169
350410
T638
E
F
Y
E
K
A
V
T
E
W
R
Q
Q
D
I
Cat
Felis silvestris
Mouse
Mus musculus
Q5H8B9
2123
234980
T635
G
L
Y
E
T
V
V
T
E
W
L
Q
R
D
I
Rat
Rattus norvegicus
Q00657
2326
251891
A675
H
N
T
G
L
R
L
A
Q
G
S
A
A
A
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417087
3168
351300
Q636
P
V
R
E
W
L
Q
Q
D
I
V
E
G
R
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796581
2335
258813
G759
N
D
L
T
V
R
E
G
Q
D
L
T
F
D
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.2
88.7
39.3
N.A.
68
20
N.A.
N.A.
39.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
27.9
Protein Similarity:
100
92.6
90.9
49.8
N.A.
80.1
35.7
N.A.
N.A.
50.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
45.2
P-Site Identity:
100
100
100
66.6
N.A.
93.3
6.6
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
73.3
N.A.
93.3
20
N.A.
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
13
0
13
0
0
0
13
13
13
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
13
0
0
0
0
0
0
13
13
0
0
0
75
0
% D
% Glu:
13
0
0
75
0
0
13
0
63
0
0
13
0
0
0
% E
% Phe:
0
13
0
0
0
0
0
0
0
0
0
0
13
0
0
% F
% Gly:
50
0
0
13
0
0
0
13
0
13
0
0
13
0
0
% G
% His:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
75
% I
% Lys:
0
0
0
0
50
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
50
13
0
13
13
13
0
0
0
63
0
0
0
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
13
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% P
% Gln:
0
0
0
0
0
0
13
13
25
0
0
63
13
0
0
% Q
% Arg:
0
0
13
0
0
25
0
0
0
0
13
0
50
13
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% S
% Thr:
0
0
13
13
13
0
0
63
0
0
0
13
0
0
0
% T
% Val:
0
13
0
0
13
50
63
0
0
0
13
0
0
0
0
% V
% Trp:
0
0
0
0
13
0
0
0
0
63
0
0
0
0
0
% W
% Tyr:
0
0
63
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _